When considering as a whole those patients who received a definitive histopathologic diagnosis, a decrease ≥ 40% in total T after gonadotrophin-suppression by gonadotropin-releasing hormone (GnRH) analogues showed a good diagnostic performance for the identification of an ovarian source of androgen excess [AUCROC (95%CI) 0.911 (0.778; 1.000)]. Here, GNRH1 is linked to hyperandrogenism.