Common adverse reactions (≥5%) in study 3b, including laboratory abnormalities, were otitis media, diarrhea, cough, sinusitis, pneumonia, upper respiratory tract infection, conjunctivitis, vomiting, pyrexia, allergic rhinitis, decreased neutrophils, increased ALT (alanine aminotransferase), increased AST (aspartate aminotransferase), hearing loss, and skin infection4. This evidence concerns the gene GPT and susceptibility to pneumonia measurement.