Forkhead box protein M1 (FoxM1) plays a significant role in the development of cancer, a significant association between FoxM1 and Tregs in GC peripheral blood was confirmed recently, FoxM1 may participate in the process of immune escape in GC through recruiting Tregs via PI3K‐Akt‐FoxO signaling axis.34 This evidence concerns the gene AKT1 and gastric cancer.