CDC73 and pachyonychia congenita: Among these, hyperparathyroidism-jaw tumor syndrome (HPT-JT) is an autosomal dominant disorder caused by <i>CDC73</i> mutations with variable clinical presentations and incomplete symptoms.<h4>Case summary</h4>The proband, diagnosed with PHPT, underwent parathyroidectomy at the age of 41 with pathological examination of parathyroid carcinoma (PC).