In clinical practice, multiple studies have confirmed that chemotherapy drugs increasing cytokine production such as TNF-α, Monocyte chemoattractant protein-1 (MCP-1), Interleukin 10 (IL-10), IL-6, and Interleukin 8 (IL-8) in cancer patients and this phenomenon is more prominent in patients who experienced dyscognition (Tsavaris et al., 2002; Meyers et al., 2005; Janelsins et al., 2012). The gene discussed is CXCL8; the disease is cancer.