SQSTM1 and myotonic dystrophy type 1: It increases TFEB myonuclear localization in skeletal muscle of myotonic dystrophy type 1 (DM1) mice, downregulates LC3-I, LC3-II, and p62 protein levels, promotes autophagy and mitophagy in the skeletal muscle, enhances skeletal muscle mitochondrial biogenesis, coordinates mitochondrial fusion and fission, and improves the overall health of skeletal muscle in DM1 mice (Mikhail et al., 2023).