A 9-week resistance training intervention reduces the accumulation of Aβ in skeletal muscle of inclusion body myositis (IBM) rats induced by peritoneal injection of chloroquine, decreased the expression of skeletal muscle mitochondrial Bax, Cyt-C, and cleaved caspase-3 proteins, and upregulates the expression of Bcl-2 proteins. This evidence concerns the gene BAX and inclusion body myositis.