Genetically predicted MPN is related to increased levels of RANTES (IVW estimate β: 0.043, 95% CI: 0.002–0.084;p = 0.039) and interleukin-10 (IVW estimate β: 0.030, 95% CI: 0.001–0.060;p = 0.041). Here, CCL5 is linked to myeloproliferative neoplasm.