IL1R1 and myeloproliferative disorder: Similarly, Øbro et al26conducted another investigation that identified significant abnormalities in the expression of epidermal growth factor, CCL11, growth regulated oncogene (GRO)-α, TGF-α, IL-1Rα, TNF-α, IL-6, IL-8, IP-10, and interferon-gamma in at least 185 patients with an MPN subtype.