Applying the IVW method, we found suggestive associations indicating that a genetically higher risk of MPN might be linked to increased levels of RANTES (β IVW = 0.043, 95% CI: [0.002, 0.084],p = 0.039;Fig. 5B) and IL-10 (β IVW = 0.030, 95% CI: [0.001, 0.060],p = 0.041;Fig. 5B). The gene discussed is IL10; the disease is myeloproliferative disorder.