Depending on the risk (low, medium, and high) groups due to how far the cancer has spread to bone marrow, bone, lymph nodes and abdomen.Surgery, muti-agent chemotherapy, myeloablative chemotherapy, radiation, total body irradiation, autologous stem cell transplantTargeted agents (33): Aurora A (34), ODC1, mTOR, pan-PI3K/mTOR, AKT, ALK, MEK, CDK, NTRK, HDAC, BCL-2, BRD4 inhibitor. The gene discussed is MAP2K7; the disease is cancer.