MYC and neoplasm: However, previous studies have consistently shown that DLBCL cell populations can be missed in flow cytometry results, likely caused by the tissue disaggregation process, fibrosis, cell fragility, necrosis, and sample size, and diagnosis-failure cases are often those with high non-lymphocyte non-granulocyte content, high T cell proportion among lymphocytes, and low tumor MYC expression (27, 38–41).