This is illustrated by their strong expression of pro-inflammatory mediators including chemokines (e.g. Ccl3, Ccl4) and members of the IL-1 family, such as Il1f9 (encoding for IL-36γ) that was specifically expressed by neutrophils and recently identified as an amplifier of pulmonary inflammation (50) (Figure 3H). The gene discussed is IL1A; the disease is inflammation.