The five nodes with the highest EIs were CESD3 “Feeling blue/depressed” (EI = 1.12), GAD1 “Nervousness or anxiety” (EI = 1.05), GAD2 “Uncontrollable worry” (EI = 1.05), GAD4 “Trouble relaxing” (EI = 1.04), and GAD3 “Worry too much” (EI = 1.02), indicating that those were the most influential symptoms. The gene discussed is GAD2; the disease is Anxiety.