For instance, FGFR3 point mutations and less frequent FGFR3 rearrangements are found in 20% of advanced urothelial carcinomas, while FGFR2/3 fusions are of particular interest in cholangiocarcinomas, in which they occur in 14% of cases [250, 251]. Here, FGFR3 is linked to cholangiocarcinoma.