The SNP that is most significantly associated with ACR—14:100812018 (AF = 5.14%; b = 0.857; p = 1.76 × 10−10) is in region 14q32.2 and mapped to the oncogenic long non-coding RNA (lncRNA) gene MEG3 (maternally expressed imprinted gene 3). The gene discussed is MEG3; the disease is atrial fibrillation.