Prognostic analysis shows that HCC patients with high TBRG4 expression have poorer overall survival(OS), disease specific survival(DSS) and progress free interval(PFI), as depicted in Fig. 2A, B, and C. In the ICGC patient’s cohort, the high expression group of TBRG4 also showed poor prognosis (Supplemental Fig. 1C). The gene discussed is TBRG4; the disease is hepatocellular carcinoma.