CD274 and neoplasm: Univariate analysis in the overall population showed that smoking, high CEA (cut-off 3.8 ng/ml), pathological stage II–III, larger tumor size, pN1/pN2, positive margin, positive LVI, positive pleural invasion, non-lepidic pathological subtype and positive PD-L1 by SP263 had a significant poorer outcome for RFS.