ITM2B and ADan amyloidosis: ITM2B mutations have been linked to four autosomal dominant neurodegenerative diseases, the Familial British Dementia (FBD) (Vidal et al, 1999), the Familial Danish Dementia (FDD) (Vidal et al, 2000) and the newly discovered Familial Chinese (Liu et al, 2021) and Familial Korean Dementias (Rhyu et al, 2023).