FBN1 and open-angle glaucoma: Aqueous humor fibrillin-1 and TGFβ2 levels in human POAG and normal control individuals were profiled based on quantitative ELISA, as shown in Fig. 4D. Human aqueous humor fibrillin-1 levels were not correlated with TGFβ2 levels in POAG (R2 = 9E−05) or normal control individuals (R2 = 0.0085; scatter plots not shown).