METTL3 and metabolic dysfunction-associated steatotic liver disease: In addition to METTL3, Yang et al.61 discovered that the expression of METTL14 is raised in NAFLD mice, and that METTL14 enhances de novo FA synthesis and lipid accumulation via raising the protein level of ATP citrate lyase and SCD1 by stabilizing m6A modification on their mRNA, consequently promoting the progression of NAFLD.