In particular, Lu et al.13 demonstrated that curcumin reduces lipopolysaccharide-induced liver damage and hepatic lipid metabolism disruption in NAFLD by boosting m6A RNA methylation, and Li et al.82 demonstrated that exenatide ameliorates hepatic steatosis by decreasing FTO gene expression and fat mass via the PI3K signaling pathway in NAFLD. Here, FTO is linked to metabolic dysfunction-associated steatotic liver disease.