METTL14 and metabolic dysfunction-associated steatotic liver disease: What’s more, Qiu et al.62 have identified that arsenic-induced NOD-like receptor protein 3 (NLRP3) inflammasome activation contributes to hepatic IR induction during arsenic-induced NAFLD, while NLRP3 mRNA stability was strengthened by METTL14-mediated m6A modification.