AKT1 and gastric cancer: In vitro, Xiao et al. [6] found that ginsenoside Rg3 sensitized GC cells to cisplatin treatment by upregulating miR-429 and inhibiting SOX2 and PI3K/AKT/mTOR signaling axes, especially when used in combination with cisplatin, which significantly increased the chemosensitivity of GC cells.