PGP and neoplasm: Dihydroartemisinin (DHA) has anti-tumor resistance effects, Zhang et al. [7] indicated that DHA can enhance autophagy by inhibiting the PI3K/AKT/mTOR pathway, as well as induce apoptosis through caspase-dependent and mitochondrial pathways and by down-regulating P-glycoprotein (P-gp) to enhance cisplatin sensitivity.