BUN - blood urea nitrogen; eGRF - estimated glomerular filtration rate; CKD - chronic kidney disease; CK - creatinine kinase; AST - aspartate aminotransferase; ALT - alanine aminotransferase; CRP - C-reactive protein; ESR - erythrocyte sedimentation rate; pRIFLE - pediatric Risk, Injury, Failure, Loss, End-Stage Renal Disease; AKI - acute kidney injury; IL-6 - interleukin 6. The gene discussed is GPT; the disease is stage 5 chronic kidney disease.