Due to the multiplicity of factors encountered in the diabetic state, along with the number of patients who suffer from diabetes, whether knowingly or unknowingly, the dental profession is challenged to not only manage patients suffering from this malady but also to educate the patient on the importance of regular oral health care [5]. Diabetes mellitus (DM) is a systemic disease consisting of several metabolic disorders resulting in chronic hyperglycemia due to impaired insulin secretion and/or insufficient tissue receptor response to serum insulin [6]. This evidence concerns the gene INS and metabolic disease.