To evaluate the effect of GPAT3‐induced LD accumulation on tumor aggressiveness under chemotherapy in vivo, we subcutaneously vaccinated the nude mice with L‐Vector or L‐GPAT3 cells, generating three groups: L‐Vector cells + Vehicle, L‐Vector cells + Oxa, and L‐GPAT3 cells + Oxa. This evidence concerns the gene GPAT3 and neoplasm.