ITGB6 expression was significantly associated with pathological grading (P=0.013), tumor size (P=0.030), location (P=0.031), N stage (P=0.002), TNM stage (P=0.002), positive lymph node rate (P=0.002), and survival status (P<0.001) (Table 1). Here, ITGB6 is linked to neoplasm.