RAC1 and neoplasm: The age surpasses the designated threshold (P=0.001), Pathological grading (P=0.016), tumor size (P<0.001), Lymphatic invasion (P=0.001), T stage (P=0.003), N stage (P<0.001), M stage (P<0.001), clinical stage (P<0.001), high αvβ6 expression (P<0.001) and high Rac1 expression (P<0.001) were identified as determinants indicating an unfavorable prognosis in the univariate analysis (as indicated in Table 3).