DTNBP1 and schizophrenia: Rodent and Drosophila models of DNTBP1 defects successfully recapitulated some of the schizophrenia hallmarks and phenotypes, such as changes in neurotransmitter release and impaired social behaviour, as well as cognitive deficits, and contributed significantly to the understanding of schizophrenia aetiology38–41,53,54 In our new behaviour paradigm, knock-down of Drosophila Dysbindin was also characterized by PPI defects.