There was no difference between the two groups with regards to age, sex, race, BMI, history of hypertension or diabetes, and the interval between index biopsy and repeat biopsy; for laboratory data, no difference was found in baseline eGFR, complement C3 and C4 level; urine studies didn’t show a statistically significant difference in baseline UPCR level between progressors and non-progressors. The gene discussed is C4A; the disease is hypertensive disorder.