GRIA3 and Cognitive impairment: Blockage of the AMPA and NMDA receptors in mature neural systems has been shown to decrease the density of dendritic spines which is then postulated to result in SCZ like symptoms and cognitive impairments (Hu et al., 2015; Poltavskaya et al., 2021) Furthermore, the published GWAS studies suggest that GRIA3 and GRIN2A to be dysregulated.