Asthmatic individuals who are obese demonstrate notably elevated levels of inflammatory markers, including blood and sputum neutrophils (176, 187), bronchial sputum eosinophil count (187), sputum IL-5 (187), blood IL-6 (187, 188), CRP (187, 189, 190), TNF-α (188), and leptin (187, 188, 190–192), in comparison to their non-obese counterparts with asthma. This evidence concerns the gene CRP and asthma.