McLeod syndrome (MLS) is an X-linked multisystem disorder caused by XK gene variants that clinically manifests with the central nervous system, neuromyopathy, angiocardiopathy, and hematology and may include progressive choreiform movements, cardiomyopathy, peripheral neuropathy, cognitive decline, and psychiatric complications (Jung et al., 2004). This evidence concerns the gene XK and McLeod neuroacanthocytosis syndrome.