Additionally, mesenchymal stem cells (MSCs) are capable of secreting EVs containing specific miRNAs, and researchers found that in CLP mice, EV miR-27b derived from MSCs was effective in hindering the recruitment of JMJD3 and NF-κB in the promoter region of proinflammatory genes, thereby reducing the expression of these genes and inhibiting sepsis (24). The gene discussed is NFKB1; the disease is Sepsis.