To investigate the expression levels of miR-30c and VIP in human colon tissues, a total of 4 active ulcerative colitis patients (male; age range: 26–35 years; the Sutherland Index range: 8–11; the modified Baron score range: 3–4) and 4 normal controls (healthy individual; males; age range: 35–66 years) were included in this study. The gene discussed is VIP; the disease is ulcerative colitis.