ACTN4 and neoplasm: Eleven DRGs, including ACTN4, ACTB, DSTN, FLNA, INF2, IQGAP1, MYH10, MYL6, MYH9, PDLIM1, and TLN1, were downregulated in tumor samples (P < 0.001), while only CAD2P was upregulated (P < 0.01) (Fig. 2F).