TNF and glioblastoma: Disruption of Myc/Max complex and inhibition of their transcriptional activity by MYCi975 alleviated TNF‐α‐induced CXCL1 production in GL261 cells (Figure 6H,I).[16] Taken together, our results suggest that TNF‐α secreted by SnAs promotes CXCL1 production by activating the transcriptional activity of c‐Myc‐Max in GBM cells.