MR1 and lung carcinoma: In order to explore the role of MR‐1 in promoting the progression of NSCLC, we integrated the data of 1014 lung cancer patients with clinical information from TCGA database, grouped by the median of PNKD, and found that it was highly correlated with the regulation of actin cytoskeleton through GSEA enrichment analysis (NES = 1.64, P = 0.004, Figure S3A, Supporting Information).