S100P has been reported to be upregulated in multiple cancers and associated with metastasis and poor prognosis.[22] Moreover, the level of S100P was further confirmed to be significantly reduced in A549, H460, and H2170 lung cancer cells with stable or transient knockdown of RBMS1 (Figure 2C and Figure S2A,B, Supporting Information). Here, RBMS1 is linked to lung carcinoma.