WNK2 and asthma: As shown in Fig. 1A, GSEA also showed that the significantly enriched hallmark terms associated with asthma included chemokine signaling pathway, cytokine–cytokine receptor interaction, Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway, and neuroactive ligand receptor interaction.