The fractions of naive CD4 T cells (p = 0.027), resting dendritic cells (p = 0.018), activated dendritic cells (p < 0.001), and eosinophils (p = 0.006) in the asthma group were remarkably higher compared with those of the healthy controls, while the fractions of memory B cells (p = 0.018), CD8 T cells (p = 0.015), activated memory CD4 T cells (p = 0.043), follicular helper T cells (p < 0.001), gamma delta T cells (p = 0.018), monocytes (p = 0.021), M0 macrophages (p = 0.006), M1 macrophages (p = 0.029), and M2 macrophages (p < 0.001) were lower in asthma. The gene discussed is CD8A; the disease is asthma.