HSL expression in human glioblastoma cell lines (SNB19, LN229, U87MG, U251MG, T98G) was detected with qRT-PCR and Western blot as well, which disclosed that the expression of HSL in glioblastoma cell lines was significantly higher than that of normal human astrocytes (NHAs) (Fig. 1F, G). This evidence concerns the gene LIPE and glioblastoma.