CD8A and neoplasm: Immunofluorescence assay showed that the oeDT adoptive immunotherapy group had the lowest expression level of PD-L1 in the mouse spleen and tumor tissue as well as the lowest enriched number of PD-L1+CD8+ double-positive T cells; this number was significantly lower than that in the shDT and wtT group (p < 0.05; Table 2, Figures S6-8).