The independent variables considered were age, history of leukoaraiosis, cognitive function, ASP score, SSR, blood uric acid, Hcy, bradykinin, coronary heart disease, hypertension, 24‐h SBPSD, dSBPSD, nSBPSD, SDNN, RMSSD, HF, and LF, which were selected based on differences observed in general data and laboratory indicators. The gene discussed is KNG1; the disease is hypertensive disorder.