Prior research indicates that elevated CRP levels in children and adolescents are associated with an increased later-life risk of developing cardiovascular diseases (Cook et al. 2000; Ford 2003; Fuligni et al. 2009), higher BMI and obesity (Cook et al. 2000; Ford 2003; Nappo et al. 2013), and depressive episodes (Danner et al. 2003). Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.