Serum TNKS2 levels were measured in patients with pituitary adenoma (n = 40) and reference (n = 40) groups, but no statistically significant difference was found (median (IQR): 1.001 (1.359) vs. 1.293 (1.382), p = 0.317). Here, TNKS2 is linked to pituitary gland adenoma.