STAT3 and neoplasm: What is more, GSVA analysis based on TCGA-BRCA dates shows high FTSJ1 expression closely related to the activation of signaling pathways such as MYC, epithelial–mesenchymal transition (EMT), TGF-β, DNA repair, IL6-JAK-STAT3, PI3K/AKT/mTOR, and Notch that promotes tumor occurrence and development, which suggests that FTSJ1 may play a certain role in the occurrence and development of TNBC (Figure 1C).