NFE2L2 and cancer: KMP’s inhibitory effects on AHR- and Nrf2-induced expression of drug-metabolizing enzymes suggest that KMP interferes with the activation of these pathways, which is relevant in the sense that the dysregulation of AHR and Nrf2 pathways has been associated with the promotion of tumor growth and resistance to chemotherapy in certain cancers, including hepatocellular carcinoma.