In addition to BC, BRCA1 is a well-established OC susceptibility gene, with a cumulative risk to age 80 years of 44% for female BRCA1 PV carriers [45]; moreover, BRCA1 PVs were recently associated with a twofold increased risk of pancreatic and stomach cancers in both sexes [34]. The gene discussed is BRCA1; the disease is gastric cancer.