BRCA1 and breast cancer: For this purpose, the large international Confluence project (https://confluence.cancer.gov, accessed on 20 December 2023) has been established, with the aim to study BC genetic susceptibility in women and men of multiple ancestries by integrating existing and new genome-wide genetic data across several BC consortia, including the BC Association Consortium (BCAC), the Consortium of Investigators of Modifiers of BrcA1/2 (CIMBA), and the newly established MBC genetics consortium (MERGE).