Because we have previously shown that DLBCL cells can secrete S1P [44], we next measured the migration of human monocytes to conditioned media from DLBCL cell lines derived from a patient with GCB DLBCL (SUDHL6) or from a patient with ABC DLBCL (OCI-Ly3). This evidence concerns the gene CD8B and diffuse large B-cell lymphoma.