S1PR1 and diffuse large B-cell lymphoma: The observation that the migration of monocytes and macrophages both in vitro and in animal models of DLBCL is dependent upon S1PR1 is in accordance with previous data showing that S1PR1 is pro-migratory for peritoneal macrophages and for bone-marrow-derived macrophages stimulated by S1P-enriched extracellular vesicles during hepatic injury [67,68].