Figure 4B presents the results for tumor size, where the same behavior can be observed, since the highest percentages of reduction were observed in the groups administered the high dose of LH (3 mg/Kg) once and twice a week, showing decreases of 72.5% and 78.34%, respectively. Regarding colon size (Figure 4C), the PC group presented a 35% decrease in length with respect to the NC, while the groups treated with the medium and high doses of LH one and two times per week avoided shortening, as there were decreases of 28%, 14.5%, and 14%, respectively. This evidence concerns the gene PLOD1 and neoplasm.