MAP2K7 and neoplasm: Further supporting a critical role for CXCL5 in neutrophil accumulation, Chao et al. found, using a KPC mouse model, that KRAS/MEK inhibition led to NF-ĸB activation and the induction of CXCL5 secretion, leading to elevated levels of CD11b+Ly6G+ and tumor progression [69].