Along with these prognostic factors, which are directly related to final histopathologic characteristics of the primary tumor, preoperative serum tumor markers in the form of Carcinoembryonic Antigen (CEA) and Carbohydrate antigen 19.9 (Ca19.9) have also been proven useful in diagnosis, guiding management, and predicting response to treatment and survival in EC [12]. Here, CEACAM5 is linked to neoplasm.