In univariate analysis (Table 2), among the analyzed novel blood neutrophil-related biomarkers, higher levels of IL-6 and IL-1RA were significantly associated with increased risk of NSCLC, with OR values of 9.339 (95% CI: 3.882, 22.646) and 7.535 (95% CI: 3.293, 17.244), respectively. The gene discussed is IL6; the disease is non-small cell lung carcinoma.