Patients stratified by high CD8+ T cell density had improved progression-free survival (logrank p = 0.02) and a reduced risk of metastatic progression after surgery for localized ccRCC (HR 0.67, 95% CI 0.47–0.96; p = 0.03) (Figure 2C). The gene discussed is CD8A; the disease is nonpapillary renal cell carcinoma.