UBASH3A and autoimmune disease: Despite the advances in understanding the roles of UBASH3 family proteins in cell signalling and activation, there is still much to learn about their precise mechanisms in the early embryonic events that might represent a basic step toward a better understanding of the effect of pathological mutations in UBASH3A and UBASHB genes and, consequently, to the design of therapeutical targets aimed at regulating their malfunctions, particularly in the context of inflammation and autoimmune diseases.